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These are images, photographs, and charts presented or developed for Low Dose Radiation Research Investigators’ Meetings. They may be used for presentations or reports. To save, right click on the picture, then choose "Save picture as."

Ionizing Radiation Dose Ranges showing the wide range of radiation doses that humans experience

(Rem) Enlarge Image.

Ionizing Radiation Dose Ranges showing the wide range of radiation doses that humans experience

(Sievert) Enlarge Image.

Classic Paradigm of Radiation Injury (High Dose)

High doses over whelm the ability to repair damage

Low Doses the microenvironment can modify the response with Other repair and protective Pathways

DNA Damage is Recorded as gH2AX Foci in The Nucleus of Human Fibroblasts Targeted With The Microbeam.

γH2AX in Targeted Human Fibroblasts

Growth Signals required to transform normal cells to cancer

Gene Mutation and Expression in Cancer

Genomic Instability

Differences in gene expression Profiles between Low and High Dose Irradiation in Brain Cells

Radiation-Induced Changes in Gene Expression as function of radiation dose

Signaling From Microenvironment

Dynamic Interactions With Microenvironment

Radiation-induced Changes in Cellular Switches

Fig. 1A

Change in gene expression as a function of time after alpha irradiation

System to study bystander effects from media transfer

Equipment to study bystander effects

3-D cell system for the study of radiation induced apoptosis

Comparison of normal and deficient cell lines induction of foci for DNA damage

Comparison of normal and deficient cell lines induction of foci for DNA damage

Chromosome painting to illustrate inter-chromosome translocations (Columbia U)

Plane of Microbeam-Irradiated Cells showing the distance the bystander response will travel

X-Ray Focusing Assembly

Microbeam for low LET ionizing radiation from the Gray Laboratory

Microbeam for low LET ionizing radiation from the Gray Laboratory

Single cells exposed to a low LET microbeam showing gammaH2AX foci

Single 3 MeV Helium Ion

Alpha microbeam developed at PNNL and moved to Texas A&M

Microprobe Beamline at the ALS

Bystander responses following exposure of a strip of cells

Bystander following exposure of a strip of cells to ionizing radiation

Higher doses showing some bystander cells in areas not “hit”

Computational Dosimetry Low-LET Microbeam Irradiation

Radial Distance, Microns

Normal Annual Exposure From Natural Radiation

Plutonium particles in the Lung of a Dog

Array Assembly & Printing

Array Printing

GenePix: Scanner by Axon Used in gene expression studies

HeLa vs Normal Human Skin Fibroblast 20K Human Chip gene expression

Micro chip with examples of changes in gene expression

Induction After Ionizing Radiation

DNA - RNA - Protiens

Regulated Proteolysis and Shedding

Micronuclei in Bystander Cells

Micronuclei in Bystander Cells

Micronuclei in cells that were not “hit” by radiation

Scoring of micronuclei in CHO cells

X-gal Staining of Forozen pKZ1 Spleen Section

Chromosome painting, Human Chromosome in CHO cell

Complex chromosome aberration in Human/CHO cell

Chromosome painting with dicentric and fragments

Low LET microbeam

Spatially-Resolved Electron Gun

Focused X-Ray Microbeam

Alpha-Particle Radiation System

FISH stained mouse chromosomes for studying chromosome aberration

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