| Principal Investigator |
Institution |
Project |
| Sally Amundson |
Columbia University Medical
Center |
Effects of Low Fluence HZE Ions on 3-Dimensional Skin Tissue |
| Carl Anderson |
Brookhaven National Laboratory |
Transcriptional and Epigenetic Responses of Human Cells to Low Dose Ionizing Radiation Identified through High Throughput ChIP-Seq Analysis |
| Edouard Azzam |
New Jersey Medical School Cancer Center |
Translationally Controlled Tumor Protein Protects against DNA Damage in Low Dose γ-Irradiated Cells
In Vivo Effects of Low Dose γ-Rays on Mitochondrial Function
|
| Susan Bailey |
Colorado State University |
Telomere Dysfunction and DNA-PKcs Deficiency: Characterization and Consequence
|
| Adayabalam Balajee |
Columbia University Medical
Center
|
Role of ATM Kinase in Ionizing Radiation Induced DNA Damage Response in Human Neural Stem/Progenitor Cells and Differentiated Cell Types
|
| Allan Balmain |
University of California San Francisco
|
Mouse Genetic Approaches to Identification of Radiation-Induced Tumor Susceptibility Genes
|
| Mary Helen Barcellos-Hoff |
New York University School of Medicine
|
Non-Targeted Effects of Low Dose Ionizing Radiation Act Via TGFβ to Promote Mammary Carcinogenesis
|
| Joel Bedford |
Colorado State University
|
Radiation Induced Chromatid-type Aberrations after Irradiation of Late-S/G2 Cells: Roles of Homologous Recombination and Non-Homologous End Joining
|
| Mina Bissell |
Lawrence Berkeley National Laboratory
|
Using Three Dimensional Cell Culture and Tissue Architecture to Monitor an Adaptive Response in Mammary Epithelial Cells
|
| David Boothman |
University of Texas Southwestern Medical Center at Dallas
|
DNA Damage Induced Clustering Expression - A Sensitive Measure of Genomic Instability
Low Dose Ionizing Radiation Induces Tumor Growth Promoting Factors in Stress-Induced Premature Senescent Fibroblasts
Low Dose IR Stimulation of TGF-β1 In Vivo and Downstream Activation of the IGF-1-sCLU Pro-Survival Expression Axis: A Bystander and Adaptive Survival Mechanism In Vivo
|
| Douglas Boreham |
McMaster University
|
Induction of DNA Damage by Low Dose PET Scans
The Mechanism of Low Dose Radiation Risk Associated with Diagnostic X-rays, PET, and Gamma-rays
|
| Simon Bouffler |
Health Protection Agency - Radiation Protection Division, Chilton, Didcot, Oxfordshire
|
Induction of DNA Damage by Low Dose PET Scans
The Mechanism of Low Dose Radiation Risk Associated with Diagnostic X-rays, PET, and Gamma-rays
|
| Cheryl Burrell |
Loma Linda University
|
Induction of DNA Damage by Low Dose PET Scans
Contribution of Tissue Level Organization to Genomic Stability Following Low Dose Gamma Irradiation
|
| David Chen |
University of Texas Southwestern Medical Center at Dallas
|
γ-Radiation Induces Distinct DNA Damage Responses in a Human Lung Epithelial Cell Three-Dimensional Culture Model
|
| Matthew Coleman |
Lawrence Livermore National Laboratory
|
Using Co-Regulation to Understand Low-Dose Ionizing Radiation Responsive Genes and Pathways
|
| Albert Davalos |
Lawrence Berkeley National Laboratory
|
Radio-Adaptive Regimen Attenuates Features of Cellular Senescence
|
| Mohan Doss |
Fox Chase Cancer Center
|
Effect of Low Dose Radiation on Antioxidant Levels In Rat Brain
|
| William Dynan |
Medical College of Georgia
|
Links Between Persistent DNA Damage, Genome Instability, and Aging
Development of a 53BP1 Transgenic Japanese Medaka Fish (Oryzias Latipes) for Investigation of Long-Term Effects of Low Dose Radiation Exposure
|
| Ignacio Fernandez-Garcia |
New York University School of Medicine
|
A Link Between Stem Cells and the EMT Phenotype Induced by IR and TGFβ
|
| Ruth Globus |
NASA Ames Research Center
|
Oxidative Stress and Skeletal Health with Low Dose, Ionizing Radiation
|
| Lee Goldstein |
Boston University School of Medicine
|
Non-Invasive Early Detection & Molecular Analysis of Low X-ray Dose Effects in the Lens
|
| Joe Gray |
Lawrence Berkeley National Laboratory
|
Mechanisms of Low-Dose and Adaptive Responses in Radiation Sensitive Tissues
A Systems Genetics Approach to Analyze the Biological Response to Low Dose Radiation
|
Joe Gray
Andrew Wyrobek
|
Lawrence Berkeley National Laboratory
|
The Low Dose Damage Response Pathways in the Mouse Mammary Glands Depends on Genotype, Tissue Compartment, Exposure Regimen, and Sampling Times
Normal Tissue Injury Responses in Mammary Glands After Low Doses or Ionizing Radiation
|
Joe Gray
Priscilla Cooper
|
Lawrence Berkeley National Laboratory
|
Molecular Mechanisms of Adaptation
|
| David Grdina
|
The University of Chicago
|
NFkB in the Thiol-Induced Adaptive Response (A)
NFkB in the Thiol-Induced Adaptive Response (B)
|
| Daila Gridley
|
Loma Linda University and Medical Center
|
Low-dose Photon and Simulated Solar Particle Event Proton Effects on Foxp3+ Treg Cells and Other Leukocytes
Low-dose Photons Modify CD4+ T Cell Signaling Response to Simulated Solar Particle Event Protons
Gene Expression Analysis of Apoptosis and Oxidative Stress in Mouse Brain After Low-dose and Acute Radiation Exposure
Long-term Effects of Low-dose Photons on Treg and Other CD4+ Lymphocyte Responses to High-dose Photons and Protons
Stem Cell Marker Expression in Mouse Lung after Exposure to Acute Photons and Protons With and Without Pre-exposure to Low-dose Photons
|
| Philip Hahnfeldt
|
Tufts University School of Medicine
|
A Programmatic Growth Control Mechanism Comprises an Additional Dynamic Affecting Low-Dose Carcinogenesis Risk
|
| Benjamin Haley
|
Northwestern University
|
Automated Data Sharing between the Janus and ERA radiobiology archives
|
| Lynn Hlatky
|
Tufts University School of Medicine
|
Evidence for a Non-Linear Dependence of Tumor Growth on Immune Response as Revealed by a Self-Metastatic Model for Tumor Growth
|
| James Jacobus
|
University of Iowa
|
LET is a Critical Factor in Accelerating Development of Lymphoma in Irradiated Bax Transgenic C57/B6 Mice
|
| Randy Jirtle
|
Duke University Medical Center
|
Low LET Radiation Alters the Fetal Epigenome of the Avy Mouse
|
| Munira Kadhim
|
Oxford Brookes University
|
Mechanisms Underlying Cellular Responses to Low Dose/Low LET Ionizing Radiation in Primary Haemopoietic Cells
|
| Norman Kleiman
|
Columbia University
|
Radiation Cataract
|
| Terumi Kohwi-Shigematsu
|
Lawrence Berkeley National Laboratory, University of
California, Berkeley
|
Genome-Wide Changes in Epigenomics Induced by X-Irradiation
|
| Michael Langston
|
University of Tennessee, Knoxville
|
Extracting Putative Gene Coexpression Networks for Low Dose Ionizing Radiation using Combinatorial Algorithms
|
| Jian Jian Li
|
University of California Davis
|
Mitochondrial Protein Influx in Low-dose Radiation-mediated Radioprotection NFkB-mediated Prosurvival Network in Low Dose Radiation-induced Radioadaptive Response in Human Skin Keratinocytes
|
| Charles Limoli
|
University of California, Irvine
|
Radioadaptation in Neural Stem Cells Exposed to Low Dose Irradiation
|
| John Miller
|
Washington State University Tri-Cities
|
Genome-wide Profiling of Histone H3 Acetylation in MCF-7 Cells in Response to Histone Deacetylase Inhibitors
|
| John Minna
|
University of Texas Southwestern Medical Center
|
Gene Expression Pathways Activated and Repair of DNA of Double Strand Breaks (DSBs) Following Low Dose Ionizing Radiation in Human Bronchial Epithelial Cells (HBECs) With and Without Defined Premalignant Oncogenic Changes
|
| William Morgan
|
Pacific Northwest National Laboratory
|
Linear and Nonlinear Tissue Signaling Mechanisms In Response to Low Dose/Low Dose-Rate Ionizing Radiation
|
| Gregory Nelson
|
Loma Linda University
|
Low Dose Ionizing Radiation Modulates Immune Function New Project Overview
|
| Kerry O'Banion
|
University of Rochester School of Medicine & Dentistry
|
Low Dose Ionizing Radiation and HZE Particle Effects on Adult Hippocampal Neurogenesis and mRNA Expression
|
| Peter O'Neill
|
University of Oxford
|
DNA Damage Pathways: Low Dose Response and Cross-Talk in TGFβ and ATM Signaling
|
| Bahram Parvin
|
Lawrence Berkeley National Laboratory
|
New Computational Methods for Characterizing Systems Biology of Low Dose and Adaptive Response
|
| David Rocke
|
University of California Davis
|
Studies of Transcriptional Changes Induced by Low Dose Ionizing Radiation in Three Human Skin Models
Genetic Profiling of Lymphoblastoid Cell Lines Sensitive to Low Dose Radiation
|
| Colette Sacksteder
|
Pacific Northwest National Laboratory
|
Molecular Mechanism Underlying Cellular Response in 3D Skin to Low Dose Radiation |
| Bobby Scott
|
Lovelace Respiratory Research Institute
|
Radiobiological Studies at LRRI Using Microgray to Milligray Gamma-Ray Doses
|
| Marianne Sowa
|
Pacific Northwest National Laboratory
|
Integrated Experimental and Computational Strategy to Develop a Predictive Understanding of Radiation Induced Matrix Remodeling in a Human Skin Tissue Model
|
| David Springer
|
Pacific Northwest National Laboratory
|
Soluble/Shed Factors Released from Skin Cells Following Low Dose Irradiation Exposure
|
| David Stenoien
|
Pacific Northwest National Laboratory
|
Analysis of Cell Signaling Mechanisms Associated With Low Dose Radiation Exposure in a Human Skin Model System
|
| Betsy Sutherland
|
University of California Davis Cancer Center
|
Processing of Clustered DNA Damage in In-vitro Biopsies of Intact Human Epidermis vs. Cultured Cells Exposed to Low Doses of X-rays |
| Pamela Sykes
|
Flinders University and Medical Centre
|
Any Apoptotic Bystander Effect Induced by Low Dose Radiation in Spleen In Vivo Must Fall Within the Homeostatic Range
Apoptosis as a Mechanism for Low Dose Radiation- and Amifostine-Mediated Chromosomal Inversion Responses
|
| Brynn Voy
|
Oak Ridge National Laboratory
|
A Systems Genetics Approach to Low Dose Radiation
|
| Ya Wang
|
Winship Cancer Institute of Emory University
|
The Ku Dependent Non-Homologous End-Joining Pathway Contributes to Low Dose Radiation Stimulated Cell Survival
|
| Thomas Weber
|
Pacific Northwest National Laboratory
|
A Role for Proline and Acid-Rich (PAR) Bzip Transcription Factors in Adaptive Response Programs
|
| Tyler Weeks
|
University of California, Davis
Lawrence Livermore National Laboratory
|
Development of Coherent Anti-Stokes Raman Scattering (CARS) Cytometry for Characterizing the Low-Dose Tissue Response
|
| Michael Weil
|
Colorado State University
|
Development of a Low Dose Rate Irradiation Facility for Long Term Animal Exposures at Colorado State University
|
| Paul Wilson
|
Lawrence Livermore National Laboratory
|
Hypersensitivity of Human and Rodent Fanconi Anemia (FA) Cells to Bystander Effect-Induced DNA Damage
|
| Gayle Woloschak
|
Northwestern University
|
The Effects of Radiation on Development of Prostate Cancer and Prostatic Hyperplasia in Canine Model
Archive Building and Interrogation of Archived Samples: New Techniques and Old Materials
Gene Copy Number Studies in Archived and Fresh Mouse Tissue Samples
Investigation of the Dog and Mouse Tissue Archives Using Complementary Imaging Techniques
|
Paul Yaswen
Bahram Parvin
|
Lawrence Berkeley National Laboratory
|
Effect of Low Dose Radiation on NF-KappaB-Mediated Transformation of Pre-Malignant MCF10A Cells
|
| Zhi-Min Yuan
|
University of Texas Health Science Center - San Antonio
|
A Functional Interaction of the C-Abl and Heat Shock Response Pathways in Radio-Adaptive Response
|
Last Update: September 2010