Howard L. Liber
Department of Environmental and Radiological Health Sciences
Colorado State University
Currently Funded Projects
Molecular Mechanisms of Radiation-Induced Genomic Instability in Human Cells
Technical Abstracts
2003 Workshop:
Delayed genomic instability in human lymphoblasts exposed to 137Cs y-rays radiation
Schwartz, J.L., Jordan, R., Lenarczyk, M. and Liber, H.L.
2002 Workshop:
Molecular Mechanisms of Radiation-Induced Genomic Instability in Human Cells.
Liber, H.L. and Schwartz, J.L.
Publications
Zhang, Y., Zhou, J., Held, K.D., Redmond, R.W., Prise, K.M., and Liber, H.L. (2008). Deficiencies of double-strand break repair factors and effects on mutagenesis in directly [gamma]-irradiated and medium-mediated bystander human lymphoblastoid cells. Radiation Research 169(2):197-206.
Zhang, Y., Zhou, J.Q., Cao, X.F., Zhang, Q., Lim, C.U.K., Ullrich, R.L., Bailey, S.M., and Liber, H.L. (2007). Partial deficiency of DNA-PKcs increases ionizing radiation-induced mutagenesis and telomere instability in human cells. Cancer Letters 250(1):63-73.
Schwartz, J.L., Jordan, R., Slovic, J., Moruzzi, A., and Liber, H.L. (2006). Chronic low dose radiation effects on radiation sensitivity, (adaptive response, low dose hypersensitivity) and genomic instability in TK6 cells. Environmental and Molecular Mutagenesis 47(6): Art. No. 434.
Zhang, Y., Lim, C.U.K., Williams, E.S., Zhou, J., Zhang, Q., Fox, M.H., Bailey, S.M., and Liber, H.L. (2005). NBS1 knockdown by small interfering RNA increases ionizing radiation mutagenesis and telomere association in human cells. Cancer Research 65(13):5544-5553.
Schwartz, J.L., Jordan, R., Evans, H.H., Lenarczyk, M., and Liber, H.L. (2003). The TP53 dependence of radiation-induced chromosome instability in human lymphoblastoid cells. Radiation Research 159(6):730–736.
Peng, Y., Zhang, Q., Nagasawa, H., Okayasu, R., Liber, H.L., and Bedford, J.S. (2002). Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing and mutation. Cancer Research 62:6400-6404.
Chuang, Y.-Y. and Liber, H.L. (1996). Effects of cell cycle position on ionizing radiation mutagenesis. I. Quantitative assays of two genetic loci in a human lymphoblastoid cell line. Radiation Research 146:494-500.
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