Daila S. Gridley
School of Medicine, Department of Microbiology and Molecular Genetics
Daila S. Gridley
Loma Linda University
Newly Funded Projects
Mechanisms of Low Dose Radiation-Induced T Helper Cell Function Abstract. Description.
Technical Abstracts
2006 Workshop:
Low Dose Photon Radiation-Induced Changes in T Helper Lymphocytes
Gridley, D.S., Rizvi, A., Luo, X., Makinde, A.Y., Rightnar, S., Tian, J., Andres, M.L., Slater, J.M., and Pecaut, M.J.
Protracted Low Dose Photon and Simulated Solar Flare Proton Effects on Cytokine/Chemokine Expression after Whole-Body Irradiation
Rizvi, A., Coutrakon, G., Slater, J.M., Pecaut, M.J., and Gridley, D.S.
2005 Workshop:
Mechanisms of Low Dose Radiation-induced T Helper Cell Function
Gridley, D.S., Green, L.M., Slater, J.M, and Pecaut, M.J.
Long-Term Effects of Whole-Body, High-LET Radiation on Blood Chemistry
Gridley, D.S., Bateman, T., Hamilton, S.A., Obenaus A., and Pecaut, M.J.
Publications
Willey, J.S., Grilly, L.G., Howard, S.H., Pecaut, M.J., Obenaus, A., Gridley, D.S., Nelson, G.A., and Bateman, T.A. (2008) Bone architectural and structural properties after Fe-56(26+) radiation-induced changes in body mass. Radiation Research 170(2):201-207.
Gridley, D.S., Rizvi, A., Luo-Owen, X., Makinde, A.Y., Coutrakon, G.B., Koss, P., Slater, J.M., and Pecaut, M.J. (2008) Variable hematopoietic responses to acute photons, protons and simulated solar particle event protons. In Vivo 22(2):159-169.
Williams, J.R., Zhang, Y., Zhou, H., Gridley, D.S., Koch, C.J., Russell, J., Slater, J.S., and Little, J.B. (2008) A quantitative overview of radiosensitivity of human tumor cells across histological type and TP53 status. International J. of Radiation Biology 84(4):253-264.
Gridley, D.S., Coutrakon, G.B., Rizvi, A., Bayeta, E.J.M., Luo-Owen, X., Makinde, A.Y., Baqai, F., Koss, P., Slater, J.M., and Pecaut, M.J. (2008) Low-dose photons modify liver response to simulated solar particle event protons. Radiation Research 169(3):280-287.
Gridley, D.S., Makinde, A.Y., Luo, X., Rizvi, A., Crapo, J.D., Dewhirst, M.W., Moeller, B.J., Pearlstein, R.D., and Slater, J.M. (2007) Radiation and a metalloporphyrin radioprotectant in a mouse prostate tumor model . Anticancer Research 27(5A):3101-3109.
Gridley, D.S., Miller, G.M., and Pecaut, M.J. (2007) Radiation and primary response to lipopolysaccharide: Bone marrow-derived cells and susceptible organs. In Vivo 21(3):453-461.
Gridley, D.S., Dutta-Roy, R., Andres, M.L., Nelson, G.A., and Pecaut, M.J. (2006) Acute effects of iron-particle radiation on immunity. Part II: Leukocyte activation, cytokines and adhesion. Radiation Research 165:78-87.
Hamilton, S.A., Pecaut, M.J., Gridley, D.S., Travis, N.D., Bandstra, E.R., Willey, J.S., Nelson, G.A., and Bateman, T.A. (2006) A murine model for bone loss from therapeutic and space-relevant sources of radiation. Journal of Applied Physiology 101(3):789-793.
Pecaut, M.J., Dutta-Roy, R., Smith, A.L., Jones, T.A., Nelson, G.A., and Gridley, D.S. (2006) Acute effects of iron-particle radiation on immunity. Part I: Population distributions. Radiation Research 165:68-77.
Luo, X., Andres, M.L., Timiryasova, T.M., Fodor, I., Slater, J.M., and Gridley, D.S. (2005) Radiation-enhanced endostatin gene expression and effects of combination treatment. Technology in Cancer Research and Treatment 4(2):193-201.
Gridley, D.S., Williams, J.R., and Slater, J.M. (2005) Low-dose/low-dose-rate radiation: A feasible strategy to improve cancer radiotherapy? Cancer Therapy 3:105-130.
Luo, X., Slater, J.M., and Gridley, D.S. (2005) Enhancement of radiation effects by pXLG-mENDO in a lung carcinoma model. International Journal Radiation Oncology Biology Physics 63(2):553-564.
Pecaut, M.J., Miller, G.M., Nelson, G.A., and Gridley, D.S. (2004) Hypergravity-induced immunodulation in a rodent model: Hematological and lymphocyte function analysis. Journal Applied Physiology 97:29-38.
Gridley, D.S., Bonnet, R.B., Bush, D.A., Franke, C., Cheek, G.A., Slater, J.D., and Slater, J.M. (2004) Time course of serum cytokines in patients receiving proton or combined photon/proton beam radiation for resectable but medically inoperable non-small-cell lung cancer. International Journal of Radiation Oncology - Biology - Physics 60(3):759-766
Gridley, D.S., and Slater, J.M. (2004) Combining gene therapy and radiation against cancer. Current Gene Therapy 4(3):231-248.
Dicello, J.F., Christian, A., Ctucinotta, F.A., Gridley, D.S., Kathirithamby, R., Mann, J., Markham, A.R., Moyers, M.F., Novak, G.R., Piantdosi, S., Ricart-Arbona, R., Simonson, D.M., Strandberg, J.D., Vazquez, M., Williams, J.R., Zhang, Y., Zhou, H., and Huso, D. (2004) In vivo mammary tumorigenesis in the Sprague-Dawley rat and rnicrodosimetric correlates. Physics Medicine Biology 49(16):3817-3830.
Pecaut, M.J., Gridley, D.S., Moyers, M.F., Rabin, B., and Nelson, G.A. (2003) "Out-of-field" effects of head-localized proton irradiation on peripheral immune parameters. In Vivo 17:513-522.
Kadhini, M.A., Green, L.M., Gridley, D.S., Murray, D.K., Tran, D.T., Pocock, D., Macdonald, D., Andres, M.A., Moyers, M.F., Goodhead, D.T., and Nelson, G.A. (Dec. 2003). Chapter 6: In vitro studies on space radiation-induced delayed genetic responses: Shielding effects. In: Radiation protection studies of international space station extravehicular activity space suits (F.A. Cucinotta, M.R. Shavers, P.B. Saganti, and J. Miller, eds.). Houston, TX : National Aeronautics and Space Administration and Johnson Space Center, NASA/TP-2003-212051, pp. 105-120.
Miller, G.M., Kim, D.W., Andres, M.L., Green, L.M., and Gridley, D.S. (2003) Changes in the activation and reconstitution of lymphocytes resulting from total-body irradiation correlate with slowed tumor growth. Oncology 65(3):229-241.
Timiryasova, T.M., Gridley, D.S., Chen, B., Andres, M.L., Dutta-Roy, R., Miller, G., Bayeta, E.J.M., and Fodor, I. (2003) Radiation enhances the anti-tumor effects of vaccinia-p53 gene therapy in glioma. Technology in Cancer Research and Treatment 2(3):223-235
Miller, G.M., Andres, M.L., and Gridley, D.S. (2003) NK cell depletion results in accelerated tumor growth and attenuates the antitumor effect of total body irradiation. International Journal Oncology 23(6):1585-1592.
Pecaut, M.J., Nelson, G.A., Bateman, T.A., Stodieck, L.S., Simske, S.J., Peters, L.L., Morony, S., Kostenuik, P.J., and Gridley, D.S. (2003) Effects of spaceflight on immunity in the C57BU6 mouse, Part 1: Immune population distributions. Journal Applied Physiology 94:2085-2094. [Featured in "Highlighted Topics" of journal.]
Gridley, D.S., Nelson, G.A., Bateman, T.A., Stodieck, L.S., Simske, S.J., Peters, L.L., Morony, S., Kostenuik, P.J., and Pecaut, M.J. (2003) Effects of spaceflight on immunity in the C57BLJ6 mouse, Part 11: Activation, cytokines, erythrocytes, and platelets. Journal Applied Physiology 94:2095-2103. [Featured in "Highlighted Topics" of journal.]
Pecaut, M.J., Gridley, D.S., and Nelson, G.A. (2003) Long term effects of low dose whole-body proton irradiation on immunity: Shielded vs unshielded. Aviation Space and Environmental Medicine 74:115-124.
Green, L.M., Patel, Z., Murray, D.K., Rightnar, S., Burell, C.G., Gridley, D.S., and Nelson, G.A. (2002) Cytoskeletal and functional changes in bioreactor assembled thyroid tissue organoids exposed to gamma radiation. Journal of Radiation Research (Tokyo) 43:S213-S218.
Gridley, D.S., Pecaut, M.J., Green, L.M., Miller, G.M., and Nelson, G.A. (2002) Hypergravity-induced immunomodulation in a rodent model: Lymphocytes and lymphoid organs. Journal of Gravitational Physiology 9(2):15-28.
George, K., Willingham, V., Wu, H., Gridley, D.S., Nelson, G., and Cucinotta, F.A. (2002) Chromosome aberrations in human lymphocytes induced by 250 MeV protons: Effects of dose, dose rate and shielding. Advances Space Research 30:891-899.
Miller, G.M., Kajioka, E.H., Andres, M.L., and Gridley, D.S. (2002) Dose and timing of total-body irradiation mediate tumor progression and immunomodulation. Oncology Research 13:9-18.
Gridley, D.S., Pecaut, M.J., Dutta-Roy, R., and Nelson, G.A. (2002) Dose and dose rate effects of whole- body proton irradiation on feukocyte populations and lymphoid organs: Part 1. Immunology Letters 80:55-66.
Pecaut, M.J., Gridley, D.S., Smith, A.L., and Nelson, G.A. (2002) Dose and dose rate effects of whole-body proton irradiation on lymphocyte blastogenesis and hematological variables: Part II. Immunology Letters 80:66-73.
Gridley, D.S., Pecaut, M.J., and Nelson, G.A. (2002) Total-body irradiation with high-LET particles: Acute and chronic effects on the immune system. American Journal of Physiology Regulatory Integrative and Comparative Physiology 282:R677-R688.
Pecaut, M.J., Nelson, G.A., and Gridley, D.S. (2001) Dose and dose rate effects of whole-body y-irradiation. 1. Lymphocytes and lymphoid organs. In Vivo 15:195-208.
Gridley, D.S., Pecaut, M.J., Miller, G.M., Moyers, M.F., and Nelson, G.A. (2001) Dose and dose rate effects of whole-body y-irradiation: I. Hematological variables and cytokines. In Vivo 15:209-216.
Nelson, G.A., Green, L.M., Gridley, D.S., Archambeau, J.-0., and Slater, J.M. (2001) Research activities at the Loma Linda University and Proton Treatment Facility: An overview. Physica Medica 17:30-33.
Kajioka, E.H., Andres, M.L., Mao, X.W., Moyers, M.F., Nelson, G.A., and Gridley, D.S. (2000) Hematological and TGF-0 variations after whole-body proton irradiation. In Vivo 14:703-708.
Kajioka, E.H., Andres, M.L., Li, J., Mao, X.W., Moyers, M.F., Nelson, G.A., Slater, J.M., and Gridley, D.S. (2000) Acute effects of whole-body proton irradiation on the immune system of the mouse. Radiation Reseach 153:587-594.
Kajioka, E.H., Andres, M.L., Nelson, G.A., and Gridley, D.S. (2000) Immunological variables in male and female C57BU6 mice from two sources. Comparative Medicine 50(3):288-291.
Pecaut, M.J., Smith, A.L., Jones, T.A., and Gridley, D.S. (2000) Modification of immunologic and hematologic variables by method of C02 euthanasia. Comparative Medicine 50(6):595-602.
Kajioka, E.H., Gheorghe, C., Li, J., Andres, M.L., Folz-Holbeck J., Abell, G.A., Slater, J.M., Nelson, G.A., and Gridley, D.S. (1999) Effects of proton and gamma radiation on lymphocyte populations and acute response to antigen. In Vivo 13(6):525-533.
Slater, J.M., Braby, L., Dicello, J., Gridley, D.S., Todd, P., and Yang, T.C. (1999) NASA Human Research Facilities: Report of the Radiation Discipline Working Group, Dept. of Radiation Medicine, Loma Linda University Medical Center. Submitted to Johnson Space Center. pp. 1-33.
» Return to the top
